PHARMACOLOGICAL EVALUATION OF CINNAMALDEHYDE AGAINST DMBA-INDUCED SKIN CANCER IN ALBINO MICE

Objectives: The primary objective of this study was to assess the pharmacological activity Cinnamaldehyde (CA) obtained from cinnamon bark in 7, 12-Dimethylbenz antharacene (DMBA)-induced skin cancer albino mice and important cell antioxidant enzymes levels which play an role cancer. Methods: Cinnamon collected obtain CA phytochemical screening extract performed. Then done with cancer, after 12 weeks observation, animal sacrificed, samples were various parameters assessed at end histopathological studies Further statistical methods applied analyze results. Results: results revealed that produces significant increase anti-oxidant such as superoxide dismutase, catalase, glutathione peroxidase content. It is also reported it has inhibited lactate dehydrogenase lipid peroxidation same time are responsible for damage. Conclusion: present shows consist anti-cancer against DMBA-induced mice.